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Pressure from multiplying cells (cyan) triggers the formation of the tooth command center known as the enamel knot (area surrounded by cyan). The knot directs tooth development within the tooth bud (yellow and magenta).
Cells Under Pressure

The physical forces that sculpt a tooth

Dr. Blake Warner studies disorders of the salivary glands. | Blake Warner
Tackling Dry Mouth, Restoring Saliva Flow

A quest to better treat Sjögren’s disease 

Computer model of a skull and temporomandibular joint.
Jaw Shape May Foretell Risk of Pain

AI tool showed a smaller jawbone may increase risk of TMDs

NIDCR News

View All
Feb 28, 2025
The Forces that Sculpt a Tooth
Research Brief
Feb 20, 2025
Tackling Dry Mouth, Restoring Saliva Flow
Research Brief
Nov 25, 2024
Our Jaw Shape May Foretell Risk of Temporomandibular Disorders
Research Brief

NIDCR’s Newsletter: Headlines

Microscopic view of mouse jaw cells.
Spring 2025
NIDCR launches Data-Driven Science Hub, forces that sculpt a tooth, tackling dry mouth, and more.

Grantee News

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Feb 28, 2025
Innate Immune Training Aggravates Inflammatory Bone Loss
University of Pennsylvania
Feb 26, 2025
Innovative CT Scan Technique Could Improve Prognosis and Treatments for Head and Neck Cancers, New Research Suggests
University of Maryland
Feb 4, 2025
How Healthy Stem Cells Turn Into Oral Cancer
University of California San Diego

Upcoming NIDCR Events

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May 28, 2025
239th National Advisory Dental & Craniofacial Research Council Meeting
Sep 10, 2025
240th National Advisory Dental & Craniofacial Research Council Meeting
Jan 21, 2026
241th National Advisory Dental & Craniofacial Research Council Meeting

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