Oral & Comprehensive Health Program

The Oral and Comprehensive Health Program aims to promote clinical research to advance knowledge in diagnosis, prevention, and management of dental, oral, and craniofacial diseases in the context of systemic health. The program supports research that evaluates the interaction between oral health and general health throughout the lifespan considering advances in science, health care integration and social influences to investigate promising directions for improving oral and comprehensive health.

More About This Program

Staff Contacts

All Staff Contacts
Margaret Grisius, DDS
Margaret M. Grisius, D.D.S.
Director
Oral & Comprehensive Health Program
Director
Clinical Technologies Research Program
(301) 451-5096
margaret.grisius@nih.gov

Funding Opportunities & Notices

View All
Title Staff Contact Opportunity number Activity Code Expiration Date
Notice to Extend Expiration Date for PAR-21-084 "NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)" NOT-DE-24-019 R03
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional) NOT-OD-25-015
Innovation Corps (I-Corps TM) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) PA-25-212 R41/R42, R43/R44, R41
Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed) NOT-OD-22-136 R15
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 R01
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Notice of Special Interest (NOSI): Climate Change and Health NOT-ES-22-006 K99/R00, R21/R33, K43
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-179 R61/R33, UG3/UH3, R34
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan NOT-OD-22-178 R61/R33, UG3/UH3, R34
Notice of Special Interest (NOSI): Availability of Administrative Supplements for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-137 333
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations NOT-MD-22-012 F99/K00, K99/R00, UG3/UH3
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R41/R42, R43/R44
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-23-032 333
Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes NOT-OD-22-167 UG3/UH3, R34, R21
Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities NOT-OD-22-154 UG3/UH3, R34, R21
Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases NOT-DA-22-048
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Notice of Special Interest (NOSI): Maternal Health and the Dental, Oral, and Craniofacial Development of their Children NOT-DE-23-005
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-23-122 R01
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-23-162 U01
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-25-239 U01
Notice of Special Interest (NOSI): Research to Address Vaccine Uptake and Implementation among Populations Experiencing Health Disparities NOT-MD-23-008
Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research NOT-OD-24-078 332
Request for Information (RFI): Food is Medicine Research Opportunities NOT-OD-23-107
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
Notice of Special Interest: R13 Support for Conferences and Scientific Meetings to Support Consensus Building for Autoimmune Disease Research Related Common Data Elements NOT-OD-24-145 R13
NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)" NOT-DE-24-009 R01
NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)" NOT-DE-24-010 R01
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020
Notice of pre-Application Technical Assistance Webinar for RFA-DE-24-003 Collaborative Science to Achieve Disruptive Innovations in Dental, Oral and Craniofacial (DOC) Research (RM1 Clinical Trial Not Allowed) NOT-DE-23-016
NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials NOT-DE-21-014
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
NIDCR Notice of Participation in PA-25-080 "NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)" NOT-DE-25-041
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) PAR-24-144 R16
Support for Research Excellence – First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) PAR-24-145 R16
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-24-152 R15
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-24-254
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-24-253 332, 333, 666
Notice of Special Interest (NOSI): Determining the Tri-directional Relationship Among Oral Health, Nutrition, and Comprehensive Health NOT-DE-24-011 R21, R01
Administrative Supplements to Promote Diversity in Research and Development Small Businesses – SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-24-255 R41/R42, R43/R44, U43
Notice of Special Interest: Women’s Health Research NOT-OD-24-079 R16, R41/R42, R43/R44
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR-25-057 UG3/UH3
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-25-346 R21
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-25-134 R15
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-25-298 R15
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR-25-105 R03
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-25-117 R01

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)