Oral & Salivary Cancer Biology Program

The Oral and Salivary Cancer Biology Program supports basic and translational research to improve detection and treatment of cancers of the Oral Cavity, Pharynx, and Salivary Glands. Basic research focuses on susceptibilities and mechanisms that influence tumor initiation, promotion, and progression. Translational research focuses on development of innovative biomarkers, novel diagnostic technologies, and appropriate human specimens to better characterize cancers and improve medical decision making and treatment response evaluation.
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Staff Contacts

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Dr. Zong Chen
Zhong Chen, M.D., Ph.D.
Director
Oral & Salivary Cancer Biology Program
(301) 529-7083
zhong.chen@nih.gov

Resources

NIDCR News

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Grantee News

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Funding Opportunities & Notices

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Title Staff Contact Opportunity number Activity Code Expiration Date
Organs-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R01 Clinical Trial Not Allowed) RFA-DE-25-001 R01
Organs-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R21 Clinical Trial Not Allowed) RFA-DE-25-002 R21
Collaborative Science to Achieve Disruptive Innovations in Dental, Oral and Craniofacial (DOC) Research (RM1 Clinical Trial Not Allowed) RFA-DE-25-004 RM1
The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) RFA-OD-22-028 R01
Notice to Extend Expiration Date for PAR-21-084 "NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)" NOT-DE-24-019 R03
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional) NOT-OD-25-015 333
Innovation Corps (I-Corps TM) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) PA-25-212 R41/R42, R43/R44, R41
Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed) NOT-OD-22-136 R15
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 R01
Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed) PAR-22-086 R21
Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R01 Clinical Trial Not Allowed) PAR-22-085 R01
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R41/R42, R43/R44
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-23-032 333
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-23-162 U01
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-23-122 R01
Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research NOT-OD-24-078 332
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed) PAR-23-255 R21
Notice of Special Interest (NOSI): Lymphatic System in Health and Disease (R01) NOT-HL-23-099
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed) PAR-23-254 R01
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
Notice of Special Interest: R13 Support for Conferences and Scientific Meetings to Support Consensus Building for Autoimmune Disease Research Related Common Data Elements NOT-OD-24-145 R13
NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)" NOT-DE-24-010 R01
NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)" NOT-DE-24-009 R01
Notice to Extend Expiration Date for PAR-20-277: Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trial Not Allowed) NOT-CA-22-093
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice of Changes to NIDCR's Clinical Terms of Award (CToA) Policy NOT-DE-19-008
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020
Notice of NIDCR Participation in RFA-CA-22-040, The Early Detection Research Network: Biomarker Characterization Centers (U2C Clinical Trial Not Allowed) NOT-DE-22-014
Notice of NIDCR's Participation in PAR-19-193 "Microbial-based Cancer Therapy-Bugs as Drugs (R01- Clinical Trial Not Allowed)" NOT-DE-19-006
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Notice of Intent to Reissue PAR-18-845 Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) and PAR-18-846 (R21 - Clinical Trial Not Allowed) as a Notice of Special Interest (NOSI) NOT-OD-21-113
NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials NOT-DE-21-014
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
NIDCR Notice of Participation in PA-25-080 "NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)" NOT-DE-25-041 R13
Notice of NIDCR's Participation in PAR-19-194 "Microbial-based Cancer Therapy-Bugs as Drugs (R21- Clinical Trial Not Allowed)" NOT-DE-19-007
Notice of pre-Application Technical Assistance Webinar for RFA-DE-24-003 Collaborative Science to Achieve Disruptive Innovations in Dental, Oral and Craniofacial (DOC) Research (RM1 Clinical Trial Not Allowed) NOT-DE-23-016
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice of NIDCR Participation in RFA-CA-21-035 The Early Detection Research Network: Biomarker Characterization Centers (U2C Clinical Trial Not Allowed) NOT-DE-21-005
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required) PAR-25-098 R01
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) PAR-24-144 R16
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required) PAR-23-170 R01
Support for Research Excellence – First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) PAR-24-145 R16
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-24-152 R15
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-24-254
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-24-253 332, 333, 666
Notice of Special Interest (NOSI): Advancing Precision Imaging for Enhanced Diagnosis and Treatment of Oral Lesions NOT-DE-25-034 R41/R42, R43/R44, UG3/UH3
Administrative Supplements to Promote Diversity in Research and Development Small Businesses – SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-24-255 R41/R42, R43/R44, U43
Notice of Special Interest: Women’s Health Research NOT-OD-24-079 R16, R41/R42, R43/R44
Notice of Special Interest (NOSI): Understanding the Basic Mechanisms of Immune-related Adverse Events (irAEs) in Cancer Immunotherapy NOT-CA-24-055 K99/R00, R15, R21

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)