Collaborative Science to Achieve Disruptive Innovations in Dental, Oral, and Craniofacial Research
Background
During the COVID-19 pandemic, researchers worldwide from different biomedical science fields worked together to find rapid solutions to an urgent global problem. Using a team science approach unites previously disconnected areas of study to answer challenging scientific questions that can lead to transformative innovations. Team science provides an opportunity to broaden the scope of inquiry based on the background, experience, and expertise of the research team members and impart the unique perspectives they each bring to bear on research questions.
NIDCR’s Response
Recognizing that a team science approach could expand scientists’ ability to pursue challenging problems in dental, oral, and craniofacial science, NIDCR issued the Collaborative Science to Achieve Disruptive Innovations in Dental, Oral, and Craniofacial Research notice of funding opportunity, or NOFO. The NOFO invited applications focused on interdisciplinary team science that tackles challenging and complex research problems that are of high priority to NIDCR and that would not be achievable by a single investigator or laboratory. Some examples of these research goals include technologies that reduce dental, oral, and craniofacial health disparities and improve health throughout the lifespan, a vaccine to reduce childhood cavities, non-opioid pain relievers, preventatives and treatments for symptoms and cooccurring conditions resulting from HIV infection, and better, longer lasting restorative systems that repair or replace damaged or missing teeth.
NIDCR-Funded Awards
In 2024, NIDCR granted two awards totaling approximately $2.5 million per year for up to five years of support.
Award Number | Principal Investigator(s) | Institution | Award Title |
---|---|---|---|
RM1-DE034220 | Randy B. Stockbridge Livia Maria Andalo-Tenuta Kevin Wood | University of Michigan at Ann Arbor | A Multiscale Approach to Develop and Apply Fluoride Efflux Inhibitors to Reverse Oral Dysbiosis and Eliminate Early Childhood Caries |
RM1-DE034233 | Jirun Sun Felicitas B. Bidlack Leyla Mirmomen Yulong Zhang | ADA Forsyth Institute, Inc. | Virtual Twin-Powered Rapid Development of Bioactive Multifunctional Dental Restoratives |
October 2024