Niki Moutsopoulos: Oral Immunity & Infection Section

Our Goal

Our goal is to implement an integrated bedside-to-bench approach to study oral mucosal immunity in health and disease. Our program leverages the strengths of the NIH intramural program on rare diseases and aims to understand human biology through the study of patients with Mendelian conditions. Our studies combine detailed clinical phenotyping of disease cohorts with basic studies in the laboratory and work on disease models with the ultimate goal of identifying therapeutic targets for human intervention. Our disease of interest is the prevalent oral inflammatory disease, periodontitis.