Clinical & Practice-Based Research Program

The Clinical and Practice-Based Research Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies of dental, oral, and craniofacial diseases and disorders. The NIDCR-supported National Dental Practice-Based Research Network is a program in which national oral health studies are conducted in dental practices on topics of importance to practitioners and their patients.
More About This Program

Staff Contacts

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Dena Fischer, D.D.S., M.S.D., M.S.
Dena Fischer, D.D.S., M.S.D., M.S.
Director
Center for Clinical Research
Director
Clinical Trials & Practice-Based Research Program
Director
Clinical Trials Program
(301) 594-4876
dena.fischer@nih.gov

NIDCR News

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Grantee News

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Funding Opportunities & Notices

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Title Staff Contact Opportunity number Activity Code Expiration Date
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
Notice to Extend Expiration Date for PAR-21-084 "NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)" NOT-DE-24-019 R03
Notice of Extension to PAR-21-160: NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-24-015 UG3/UH3
Notice of Extension to PAR-22-068: Continuation or Revision of NIDCR Clinical Trial Implementation Cooperative Agreement (UH3 Clinical Trial Required) NOT-DE-24-016 UH3
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional) NOT-OD-25-015
Innovation Corps (I-Corps TM) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) PA-25-212 R41/R42, R43/R44, R41
Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed) NOT-OD-22-136 R15
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 R01
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R41/R42, R43/R44
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-23-032 333
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-23-162 U01
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-23-122 R01
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-25-239 U01
Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research NOT-OD-24-078 332
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
Notice of Special Interest: R13 Support for Conferences and Scientific Meetings to Support Consensus Building for Autoimmune Disease Research Related Common Data Elements NOT-OD-24-145 R13
NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)" NOT-DE-24-010 R01
NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)" NOT-DE-24-009 R01
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials NOT-DE-21-014
Notice of Technical Assistance Webinar for RFA-DE-23-012 Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED) NOT-DE-22-017
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-18-016
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-20-037
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
NIDCR Notice of Participation in PA-25-080 "NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)" NOT-DE-25-041
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
Notice of Changes to NIDCR's Clinical Terms of Award (CToA) Policy NOT-DE-19-008
Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) NOT-DE-20-024
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020
Notice of Intent to Publish a Funding Opportunity Announcement for Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED) (U01 Clinical Trial Not Allowed) NOT-DE-22-013
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) PAR-24-144 R16
Support for Research Excellence – First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) PAR-24-145 R16
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-24-152 R15
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-24-254
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-24-253 332, 333, 666
Administrative Supplements to Promote Diversity in Research and Development Small Businesses – SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-24-255 R41/R42, R43/R44, U43
Notice of Special Interest: Women’s Health Research NOT-OD-24-079 R16, R41/R42, R43/R44
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR-25-105 R03
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-25-117 R01
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-25-134 R15
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-25-298 R15

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)